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Fold change in proliferation rate of EA.Hy926 cells after treatment with anti-VEGFA siRNA/R6p-cRGD polyplexes analyzed by Alamar blue assay (a) and by crystal violet assay (b); *—p < 0.05, **—p < 0.01 when compared with cells treated by mock siRNA/R6p-cRGD polyplexes. The data are shown as the mean ± S.D. of n = 15 individual samples from five independent experiments; statistical significance was assessed by ordinary one-way ANOVA.
