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Inhibition of PI3K reduced hypertrophic growth: Cardiomyocytes were transfected with YB-1 siRNA or were not transfected. The protein synthesis rate was measured 48 h after transfection with siRNA, preceded by 24 h of PE (10 µM) stimulation (n = 5 cardiomyocyte preparations). Data are presented as the means ± SEMs. Key: * p < 0.05, ** p < 0.01, *** p < 0.001, compared to control cells or as indicated by the bar.
