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. 2023 Dec 19;25(1):15. doi: 10.3390/ijms25010015

Figure 1.

Figure 1

EV expression of pro-inflammatory mRNAs (a) and miRNAs (b). Blue bars: EVs extracted from the supernatants of microglial cells cultured in physiological conditions (ctrl); red bars: EVs extracted from the supernatants of M1-activated microglial cells (M1); green bars: EVs extracted from the supernatants of microglial cells cultured in the presence of thiamine (T); purple bars: EVs extracted from the supernatants of microglial cells cultured in M1 conditions plus thiamine (M1+T). Mean ± SD of 5 independent experiments. * = p < 0.05 vs. ctrl and M1+T; £ = p <0.005 vs. ctrl and M1+T; $ = p < 0.001 vs. ctrl and M1+T.