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. 2023 Dec 19;25(1):15. doi: 10.3390/ijms25010015

Figure 3.

Figure 3

Release of pro-inflammatory/pro-angiogenic factors by (a) HRPs and (b) HRECs following exposure to microglia-derived EVs. Blue bars: cells exposed to EVs extracted from the supernatants of microglial cells cultured in physiological conditions (ctrl); red bars: cells exposed to EVs extracted from the supernatants of M1-activated microglial cells (M1); green bars: cells exposed to EVs extracted from the supernatants of microglial cells cultured in the presence of thiamine (T); purple bars: cells exposed to EVs extracted from the supernatants of microglial cells cultured in M1 conditions plus thiamine (M1+T). Mean ± SD of 5 independent experiments. * = p < 0.05 vs. ctrl and M1+T; $ = p < 0.005 vs. ctrl and M1+T; # = p < 0.05 vs. ctrl.