Size (nm) and concentration (number × 1011/mL) (mean ± SD of 5 independent measures) of EVs derived from human microglia exposed to different stimuli. ctrl = EVs extracted from the supernatants of microglial cells cultured in physiological conditions; M1 = EVs extracted from the supernatants of M1-activated microglial cells; T = EV extracted from the supernatants of microglial cells cultured in the presence of thiamine; M1+T = EVs extracted from the supernatants microglial cells cultured in M1 conditions plus thiamine. * p < 0.05 vs. ctrl and M1.