Table 2.

Comparison of folliculogenesis and oogenesis-specific genes identified in this review with previous putative genes sensitive to the environment (PCOS, maternal age, IVM, cryoconservation). Only DEGs retrieved in >2 studies for each factor were considered to increase robustness of the analysis.

Factor	Folliculogenesis Cross-Checking	GV-to-MII Cross-Checking
PCOS	ARHGAP18 ATRX CNOT6 EEA1 KLHL32 LAMP3 LRRTM4 POMP RASA1 SCAMP2 SERPINB5 UBE2V2 ZDHHC6	AMOT ARHGAP18 ATRX C3orf14 CASP8 CNOT6 CTNND1 EEA1 FKBP4 NFRKB NIF3L1 PRPS2 SERPINB5 TNRC6A
Maternal age	ABHD5 ATRX C12orf75 C1orf146 C5orf58 CNIH4 COX7B DEAF1 GCA GPX1 HAL LGALS12 LSM8 MRFAP1 MRPL22 NDUFA1 NDUFB6 PIN1 PIR PLEKHF2 POMZP3 PTBP2 RAD23B SAA1 SCGB3A2 SLC10A3 SNAP23 STYK1 TICAM1 TMEM65 TSPAN13 TSPYL5 TUBA3E TXNDC12 UCHL3 ZAR1L	ABHD5 ARPC1A ARPC3 ATRX BDH2 C5orf58 CFL2 CNIH4 CYB5A DYNLL1 EIF6 ELP1 LGALS12 LSM6 MRPL22 MYL12A NDUFA1 NDUFAF6 NDUFS6 PDCD5 PIN1 PPA1 PPRC1 PSMB1 PTS RECQL4 RMI2 SCCPDH SNRPA1 SRRM1 TMEM65 UCHL3
IVM	ATP5MG DCTN6 LYPLAL1 NFE2L2 PAOX PCF11 TAF1A	DAZL DDX59 DEPDC7 EXOSC8 MKKS MRPL20 PSMB1
Oocyte cryoconservation	FOXO3B PRKCSH RSPH4A SF3A2 TRPC3 TYMS UBXN4 USP4 ZWINT	DYSF UBXN4 ZNF530

DEGs: differentially expressed genes; IVM: in vitro maturation; PCOS: polycystic ovary syndrome.