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. 2023 Dec 31;25(1):551. doi: 10.3390/ijms25010551

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Hypothetical homologous recombination between the pP62BP1 R-M systems. (a) Theoretical model of DNA recombination between homologous sequences found with the same orientation in a circular DNA molecule. (b) Predicted products of the homologous recombination between the pP62BP1 R-M systems. Hypothetical ‘hybrid’ R-M systems (hR-M) are indicated. Neither of the predicted products was identified experimentally. Binding sites for primers used for PCR-based screening are indicated (cf. Figure S7). Colors correspond to the main genetic modules of the plasmid.