Table 2.
Databases and web servers for documenting and analyzing RNA editing sites (RESs).
Database | Description | RES Amount | Species | URL |
---|---|---|---|---|
dbRES [176] | Collection of known RNA editing sites with comprehensive annotations. | 5437 | 96 species covering plant, metazoan, protozoa, fungi, and virus | http://bioinfo.au.tsinghua.edu.cn/dbRES [Accessed on 12 December 2023] |
e23D [27] | Database of RES mapped to evolutionary-related 3D protein structures. | 2,576,459 (human) 8823 (mouse) 5025 (fly) |
Human Mouse Fly |
|
GPEdit [29] | Collection of RNA Editing quantitative trait loci (edQTL) in cancers. | 320,029 (edQTLs) | Human (33 cancer types) | https://hanlaboratory.com/GPEdit/ [Accessed on 12 December 2023] |
LNCediting v1.0 [181] | RES in lncRNAs with their effects on lncRNA secondary structures and lncRNA–miRNA interactions. | 199,991 (human) 1922 (mouse) 165 (rhesus) 1829 (fly) |
Human Mouse Rhesus Fly |
http://bioinfo.life.hust.edu.cn/LNCediting/ [Accessed on 12 December 2023] |
miR-EdiTar [180] | Predicted A-I-edited miRNA binding sites. | 10,571 | Human | |
miREDB [182] | RNA editing on miRNAs. | 4162 in around 80% of pre-miRNAs and 574 in mature miRNAs | Human Mouse Drosophila |
|
PRES [185] | Web server for downstream functional perturbations at RES. | - | Human | http://bio-bigdata.hrbmu.edu.cn/PRES/ [Accessed on 12 December 2023] |
PRESDB [179] | Pig genome-wide RNA-editing investigation. | 59,472 | Pig | https://presdb.deepomics.org/ [Accessed on 12 December 2023] |
RADAR v1/2 [53] | Collection of RESs, including tissue-specific editing levels. | Humans (1,379,403) Mouse (8108) Drosophila (2698) |
Human Mouse Drosophila |
http://rnaedit.com/ [Accessed on 12 December 2023] |
REDIportal v1/2 [28,186] | ATLAS of RESs in human tissues and other organisms. | 16 million (human) 107,094 (mouse) |
Human (31 tissues) Mouse (2 tissues) |
http://srv00.recas.ba.infn.it/atlas/ http://srv00.recas.ba.infn.it/atlas/index.html [Accessed on 12 December 2023] |
REDR [187] | Potential regulation of RNA editing in drug resistance to 18 anticancer drugs. | 7157 DESs from 98,127 informative RESs | Human (6 cancer types) | http://www.jianglab.cn/REDR/ [Accessed on 12 December 2023] |
REIA [183] | Interactive web server that analyzes and visualizes RESs in cancers. | 8,447,588 | Human (34 cancer types) | http://bioinfo-sysu.com/reia [Accessed on 12 December 2023] |