AAV	adeno-associated virus
ACC	agenesis of the corpus callosum
ADHD	attention deficit hyperactivity disorder
AGC1	aspartate glutamate carrier 1
ASO	antisense oligonucleotides
AEDs	antiepileptic drugs
CBD	cannabidiol
CDG	congenital disorder of glycosylation
CONTAIN	ClObazam in patieNTs with LennoxGAstaut SyNdrome
CRISPR/CAS	clustered regularly interspaced short palindromic repeat-associated nucleases
DEs	developmental encephalopathies
DEE	developmental and epileptic encephalopathies
DECAM	developmental delay, epileptic encephalopathy, cerebral atrophy, and abnormal myelination
DRE	drug-resistant epilepsy
DS	Dravet syndrome
EEs	epileptic encephalopathies
EEG	electroencephalography
EFMR	epilepsy and mental retardation restricted to females
EEOC	epileptic encephalopathy, childhood onset
FDA	Food and Drug Administration
GABA	γ-aminobutyric acid
GEFS+	genetic epilepsy with febrile seizures plus
GOF	gain-of-function
GOT2	glutamate oxaloacetate transaminase
GPIBD	glycophosphatidylinositol biosynthesis defect
IECEE	epileptic encephalopathy, infantile or early childhood
IGF-1	insulin-like growth factor 1
ILAE	International League Against Epilepsy
ISSX2	infantile spasm syndrome, X-linked 2
IQ	intelligence quotient
LGS	Lennox Gastaut syndrome
LISX2	lissencephaly, X-linked, 2
LOF	loss-of-function
MCAHS	multiple congenital anomalies–hypotonia–seizures syndrome
MCSZ	microcephaly, seizures, and developmental delay
mRNA	messenger RNA
MRX	mental retardation, X-linked
MRXS1	mental retardation, X-linked, syndromic 1
MRI	magnetic resonance imaging
NCSE	nonconvulsive status epilepticus
PV	parvalbumin
PRTS	Partington syndrome
RNA	ribonucleic acid
SCN1A	voltage-gated channel alpha subunit 1
SCN9A	voltage-gated channel α subunit 9
SE	status epilepticus
SMA	spinal muscular atrophy
SMEI	severe myoclonic epilepsy in infancy
SST	somatostatin
SUDEP	sudden unexpected death in epilepsy
TALE	transcription activator-like effector
TALENs	transcription activator-like effector nucleases
TANGO	targeted augmentation of nuclear gene output
TSH	thyroid-stimulating hormone
VGSC	voltage-gated sodium channel
VNS	vagus nerve stimulation
VPA	valproic acid
XLAG	X-linked lissencephaly with ambiguous genitalia
XLID29	intellectual developmental disorder, X-linked 29
ZFNs	zinc-finger nucleases
5-HT	5-hydroxytryptamine
5-HT3aR	serotonin receptor 3a