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Effect of ISO on protein expression in U27 cells and U27−/− cells. (A,B) p-EGFR, p-STAT3, and PD-L1 expression in (A) U27 and (B) U27−/− cells with different concentrations of ISO. (C,D) p-EGFR, p-STAT3, and PD-L1 expression in (C) U27 and (D) U27−/− cells exposed to ISO for different lengths of time. (E) p-EGFR, p-STAT3, and PD-L1 expression in U27 and U27−/− cell exposed to either ISO or gefitinib. Data are mean ± SD. * p < 0.05; ** p < 0.01 on one-way ANOVA.
