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(A) The synthesis pathway for single-drug and combined-PGA-drug conjugates. (B) Representative 1H-NMR spectra recorded in D2O at 500 MHz. (C) A representative SEC chromatogram showing parental PGA and PGA-DOX, PGA-(G-AGM)LL, and PGA-(G-AGM)LL-DOX conjugates with UV detection at 260 nm [57].
