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(A) The γ-PGA-CA-Pt(IV) was converted to Pt(II) in acidic environment, and the killing rate of Pt(IV) was enhanced after pre-incubation with GSH [65]. (B) CPTP/CDDP release CPT diagram [63]. (C) Schematic diagram of enhancing anti-tumor effect of PLG-CDDP nano-agent [66]. (D) Schematic illustration of cisplatin (CDDP)-loaded and TFR-targeted drug delivery systems constructed via the self-assembly method [64].
