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Virulence studies. Each study included 10 mice per strain in two independent experiments. Mice were injected intravenously with 1.5 × 105 conidia. Mouse mortality was monitored daily for 21 days. Strains: B-5233, the wild-type strain; B-5233/RGD12-8, the alb1 disruptant; RGD12-8/PKS33-3, the alb1-complemented strain. P < 0.05 for comparison of the alb1 disruptant to B-5233 or the alb1-complemented strain (Kaplan-Meier analysis).
