Comparison of the putative N.
meningitidis LbpB protein sequence with sequences of TbpB proteins
from related organisms. The putative amino acid sequence of
N. meningitidis B16B6 LbpB was compared to the known
amino acid sequences of other known TbpBs, namely, N.
meningitidis B16B6 and M982 (29), N.
gonorrhoeae FA19 (2), A. pleuropneumoniae
H49 (19) and S-tp1 (18), P.
haemolytica H196 (35), and H. influenzae
DL63 (20). The basic alignment was performed by using the
program DNAsis. ∗, homology with at least three other TbpBs; Δ,
absolute homology with all selected TbpBs. Shaded boxes indicate
negatively charged regions of LbpB not present in TbpBs; unshaded box
indicates proposed site of P-loop motif.