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. 2024 Jan 10;14:968. doi: 10.1038/s41598-023-50351-6

Table 1.

Summary information on SNPs associated with dark chocolate intake in the Mendelian randomization analyses.

SNP Nearby gene EA OA EAF Beta SE p value F-statistic
rs10799451 PRSS38 C T 0.9529 -0.0308 0.0055 2.60E-08 31.0
rs61788541 DPYD T C 0.1761 -0.0139 0.0030 4.10E-06 21.2
rs75633229 NCKAP5 G T 0.0076 0.0651 0.0135 1.30E-06 23.4
rs115832742 SORCS2 C T 0.0090 0.0654 0.0123 9.90E-08 28.4
rs10462943 MAT2B T C 0.3667 -0.0119 0.0024 6.10E-07 24.9
rs114103245 SNCAIP G A 0.0099 0.0534 0.0116 4.30E-06 21.1
rs10806742 PARK2 C T 0.3717 0.0112 0.0024 3.40E-06 21.6
rs145537395 SRSF3 A G 0.0136 0.0491 0.0102 1.30E-06 23.4
rs259386 ADGB C T 0.6204 -0.0109 0.0024 4.70E-06 21.0
rs6916329 SLC2A12 C T 0.0160 0.0455 0.0091 7.10E-07 24.6
rs78920357 RPS6KA2 C T 0.0617 -0.0241 0.0050 1.80E-06 22.8
rs10273549 LSMEM1 A G 0.0638 0.0224 0.0047 1.70E-06 22.9
rs6951020 RP11-507K12.1 C T 0.9228 -0.0210 0.0043 1.10E-06 23.8
rs7008560 NCALD A T 0.0230 0.0376 0.0077 9.80E-07 24.0
rs17143632 GATA3 A G 0.0059 0.0737 0.0149 8.00E-07 24.4
rs76124460 KCNMA1 A G 0.0098 0.0612 0.0121 3.90E-07 25.7
rs71469535 ACER3 T C 0.0159 0.0481 0.0100 1.40E-06 23.3
rs146635941 KLHL1 T C 0.0189 0.0485 0.0093 2.10E-07 27.0
rs150993006 PCDH9 T A 0.0108 0.0555 0.0119 3.10E-06 21.7
rs112868306 SERPINB8 C T 0.0089 0.0573 0.0124 3.90E-06 21.3
rs5760827 KIAA1671 G A 0.7775 -0.0135 0.0029 3.10E-06 21.7

SNP single-nucleotide polymorphism, EA effect allele, OA other allele, EAF effect allele frequency, SE standard error.