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. 2024 Jan 10;15:433. doi: 10.1038/s41467-023-44467-6

Fig. 1. Study workflow.

Fig. 1

In an overlapping set of kidney samples, tissue was interrogated by laser microdissection-guided whole genome bisulfite sequencing (WGBS), by multiome single nucleus Assay for Transposase-Accessible Chromatin for sequencing (snATAC-seq) and single nucleus RNA sequencing (snRNAseq) after cell disaggregation, and by Cleavage Under Targets & Release Using Nuclease (CUT&RUN) of kidney cortex. Datasets were aligned in the human genome 38 to create an integrated epigenomic atlas.