Table 1.
Baseline characteristics of the study population according to the TyG-BMI index.
| Variables | Total (n = 2648) | Q1 (n = 883) | Q2 (n = 882) | Q3 (n = 883) | p-value |
|---|---|---|---|---|---|
| TyG-BMI | 224.01(204.16–247.48) | 193.79(180.23–204.12) | 224.01(217.82–231.27) | 258.00(247.48–277.93) | < 0.001 |
| Age, years | 59.34 ± 11.40 | 62.15 ± 11.50 | 59.64 ± 10.93 | 56.24 ± 11.00 | < 0.001 |
| Male | 2,144 (81.0) | 705 (79.8) | 719 (81.5) | 720 (81.5) | 0.580 |
| Smoker | 1,633 (61.7) | 533 (60.4) | 533 (60.4) | 567 (64.2) | 0.163 |
| Drinker | 870 (32.9) | 254 (28.8) | 293 (33.2) | 323 (36.6) | 0.002 |
| Hypertension | 1,205 (45.5) | 328 (37.1) | 428 (48.5) | 449 (50.8) | < 0.001 |
| Diabetes | 565 (21.3) | 112 (12.7) | 160 (18.1) | 293 (33.2) | < 0.001 |
| Previous PCI | 263 (9.9) | 73 (8.3) | 85 (9.6) | 105 (11.9) | 0.037 |
| Previous MI | 360 (13.6) | 114 (12.9) | 99 (11.2) | 147 (16.6) | 0.003 |
| Previous stroke | 205 (7.7) | 76 (8.6) | 66 (7.5) | 63 (7.1) | 0.481 |
| Previous arrhythmia | 315 (11.9) | 98 (11.1) | 104 (11.8) | 113 (12.8) | 0.541 |
| FH-CAD | 164 (6.2) | 50 (5.7) | 57 (6.5) | 57 (6.5) | 0.725 |
| BMI, kg/m2 | 25.06 ± 4.45 | 22.00 ± 2.10 | 24.62 ± 1.34 | 28.57 ± 5.60 | < 0.001 |
| SBP, mm Hg | 127.52 ± 21.63 | 125.27 ± 20.78 | 128.66 ± 21.71 | 128.62 ± 22.22 | < 0.001 |
| DBP, mmHg | 77.02 ± 13.65 | 75.30 ± 12.92 | 77.37 ± 13.60 | 78.40 ± 14.23 | < 0.001 |
| HR, bpm | 75.68 ± 16.90 | 74.36 ± 16.21 | 76.28 ± 17.35 | 76.42 ± 17.06 | 0.001 |
| GRACE score | 142(124–162) | 149(130–167) | 143.50(126–162) | 134(119–156) | < 0.001 |
| FPG, mmol/L | 7.85 ± 3.44 | 6.75 ± 2.35 | 7.86 ± 3.44 | 8.94 ± 3.97 | < 0.001 |
| BUN, mmol/L | 6.07 ± 2.44 | 6.25 ± 2.94 | 5.89 ± 1.93 | 6.07 ± 2.33 | 0.010 |
| Ccr, ml/min | 86.02 ± 24.04 | 86.82 ± 25.12 | 85.48 ± 24.05 | 85.75 ± 22.89 | 0.213 |
| TG, mmol/L | 1.54(1.09–2.25) | 1.10(0.82–1.51) | 1.60(1.20–2.14) | 2.17(1.53–3.07) | < 0.001 |
| TC, mmol/L | 4.50(3.81–5.27) | 4.30(3.62–4.97) | 4.54(3.85–5.33) | 4.70(3.99–5.43) | < 0.001 |
| LDL-C, mmol/L | 2.42(2.02–2.91) | 2.32(1.96–2.77) | 2.45(2.03–2.93) | 2.48(2.11–3.00) | < 0.001 |
| HDL-C, mmol/L | 1.29(1.02–1.57) | 1.24(1.01–1.48) | 1.31(1.03–1.60) | 1.32(1.03–1.62) | < 0.001 |
| D-dimer, ng/ml | 0.39 ± 0.34 | 0.38 ± 0.34 | 0.40 ± 0.37 | 0.40 ± 0.30 | 0.007 |
| TnT, ng/ml | 0.21(0.05–0.95) | 0.20(0.05–1.04) | 0.24(0.05–1.00) | 0.18(0.05–0.75) | 0.051 |
| CK, U/L | 165.00(78.75–615.25) | 160.00(74.50–578.50) | 187.00(85.00–720.75) | 155.00(77.00–531.50) | 0.009 |
| CK-MB, U/L | 19.00(11.00–56.00) | 19.00(12.00–54.00) | 21.00(12.00–68.50) | 17.00(11.00–49.00) | 0.008 |
| LVEF | 0.57 ± 0.10 | 0.57 ± 0.10 | 0.56 ± 0.09 | 0.58 ± 0.09 | 0.003 |
| LVEDD, mm | 48.65 ± 5.85 | 48.14 ± 6.14 | 48.61 ± 5.61 | 49.20 ± 5.74 | < 0.001 |
| Killip class ≥ 2 | 571(21.6) | 177 (20.0%) | 212 (24.0%) | 182 (20.6%) | 0.088 |
| Anterior MI on ECG | 1,427(53.9%) | 490(55.5%) | 484(54.9%) | 453(51.3%) | 0.162 |
| TIMI grade 0–1 fow before PCI | 2,494(94.2%) | 833(94.3%) | 830(94.1%) | 831(94.1%) | 0.972 |
| Time from symptom onset to hospital arrival, min | 126.47 ± 146.23 | 125.20 ± 137.75 | 115.92 ± 122.42 | 138.28 ± 173.15 | 0.045 |
| Stenting | 2,591 (97.8) | 868 (98.3) | 867 (98.3) | 856 (96.9) | 0.076 |
| Multi-vessel disease | 1,773 (67.0) | 592 (67.0) | 598 (67.8) | 583 (66.0) | 0.700 |
| Thrombolysis | 414 (15.6) | 132 (14.9) | 146 (16.6) | 136 (15.4) | 0.600 |
| Timely PCI | 878 (33.2) | 272 (30.8) | 318 (36.1) | 288 (32.6) | 0.059 |
| Length of stay, days | 8.71 ± 10.47 | 8.66 ± 10.46 | 8.39 ± 5.10 | 9.08 ± 13.90 | 0.900 |
| Medical treatment | |||||
| ACEI/ARB | 1,220(46.1) | 390 (44.2) | 422 (47.8) | 408(46.2) | 0.299 |
| Beta-blockers | 1,401 (52.9) | 438 (49.6) | 468(53.1) | 495 (56.1) | 0.025 |
| CCB | 152 (5.7) | 56 (6.3) | 63 (7.1) | 33 (3.7) | 0.006 |
Data were expressed as mean ± SD, median (with interquartile range), or n (%).
TyG-BMI Triglyceride glucose-body mass index, PCI percutaneous coronary intervention, MI myocardial infarction, FH-CAD family history of coronary artery disease, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, HR heart rate, GRACE Score Global Registry of Acute Coronary Events Score, FPG Fasting plasma glucose, BUN Blood urea nitrogen, Ccr creatinine clearance rate, TG triglyceride, TC total cholesterol, LDL-C low density lipoprotein cholesterol, HDL-C high density lipoprotein cholesterol, TnT Troponin T, CK creatine kinase, CK-MB creatine kinase-MB, LVEF left ventricle ejection fraction, LVEDD left ventricular end-diastolic dimension, ACEI angiotensin II coenzyme inhibitor, ARB angiotensin II receptor blocker, CCB calcium channel blocker.