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. 2023 Jun 22;42(1):92–132. doi: 10.5534/wjmh.230034

Table 5. Results of the before-after varicocele repair analysis of conventional semen parameters.

Parameter Random Before (n) After (n) SMD 95% CI p Heterogeneity Publication bias
I2 p Egger’s test
Semen volume Random 12,566 10,825 0.203 0.129 to 0.278 <0.001 83.62% <0.001 0.3329
Sperm concentration Random 32,577 31,771 1.590 1.474 to1.706 <0.001 97.86% <0.0001 <0.0001
Total sperm count Random 5,593 5,337 1.824 1.526 to 2.121 <0.0001 97.88% <0.0001 0.0063
TMSC Random 6,396 6,274 1.643 1.318 to 1.968 <0.001 98.65% <0.0001 0.0003
Progressive sperm motility Random 10,454 10,252 1.845 1.537 to 2.153 <0.001 98.97% <0.0001 <0.0001
Total sperm motility Random 22,326 21,898 1.613 1.467 to 1.759 <0.001 97.98% <0.0001 <0.0001
Sperm morphology Random 21,979 21,335 1.066 0.922 to 1.211 <0.001 97.87% <0.001 0.1864
Sperm vitality Random 597 555 -1.310 -2.112 to -0.509 0.001 98.50% <0.0001 0.0807

SMD: standard mean difference, TMSC: total motile sperm count.