Table 1.
Clinical variables and outcomes for 101 young children with intracranial ependymoma.
| Number | Time | |
|---|---|---|
| Age at RT | ||
| Diagnosis | 1.68 years (0.01–3.02 years) | |
| Radiation Therapy | 2.12 years (0.89–3.10 years) | |
| Last Follow-up | 20.81 years (7.46–26.84 years) | |
| Sex | ||
| M | 55 | |
| F | 46 | |
| Race/Ethnicity | ||
| Asian | 4 | |
| Black | 9 | |
| Hispanic | 4 | |
| Other | 4 | |
| White | 80 | |
| Extent of Resection | ||
| Gross-total Resection | 83 | |
| Near-total Resection | 7 | |
| Sub-total Resection | 11 | |
| Clinical Target Volume Margin | ||
| 0.5cm | 22 | |
| 1.0cm | 79 | |
| Total Dose | ||
| 54.0 Gy | 28 | |
| 59.4 Gy | 73 | |
| Tumor Location | ||
| Infratentorial | 90 | |
| Supratentorial | 11 | |
| Grade | ||
| Classic | 30 | |
| Anaplastic | 71 | |
| Shunt | ||
| None | 49 | |
| Yes | 52 | |
| Cause of Death | ||
| Tumor Progression | 24 | |
| High-grade Glioma | 6 | |
| Necrosis | 2 | |
| Shunt Failure | 1 | |
| Anaphylaxis | 1 | |
| Pattern of Failure | ||
| Local | 17 | 2.02 years (0.86–9.46 years) |
| Distant | 11 | 1.70 years (0.39–4.48 years) |
| Local and Distant | 6 | 0.89 years (0.63–2.90 years) |
| Secondary Tumor | ||
| Benign Thyroid Nodule | 5 | 14.4 years (4.00–16.19 years) † |
| Meningiomatosis | 1 | 4.92 years |
| Cholesteatoma | 1 | 13.01 years |
| Low-grade glioma | 1 | 2.80 years |
| High-grade Glioma | 6 | 9.79 years (4.05–14.53 years) ‡ |
| Meningioma | 7 | 14.25 years (6.19–18.39 years) |
| Papillary Thyroid Cancer | 3 | 9.16 years (6.84–11.32 years) |
| Vestibular Schwannoma | 1 | 11.14 years |
†
Two patients who developed thyroid nodules in addition to meningioma are included.
‡
Two re-irradiated patients who developed high-grade glioma 8.39 and 14.53 years after their initial treatment with radiation therapy are included.