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. Author manuscript; available in PMC: 2024 Jan 11.
Published in final edited form as: Obesity (Silver Spring). 2021 Feb;29(2):337–349. doi: 10.1002/oby.23065

TABLE 1.

Differential mRNA levels (fold-change) of PPARα-target genes in mouse liver

Gene Gene product function Control + kynurenine diet/control dieta Western diet/control dieta

Elovl5 Elongates long fatty acids 1.72 NC
G0s2 Regulates adipocyte lipase and lipolysis 2.19 2.18
Retsat Modulates lipid metabolism and adiposity 1.55 1.65
Scd1 Catalyzes monounsaturated fatty acids 2.42 2.60

NC, no significant change.

a

Microarray results (P ≤ 0.05) for male B6 mice (n = 3/experimental group) on a 20-week, ad libitum diet regimen.