Table 2 –

Thrombus characteristics on a thrombus-region level

Variable	Plaque rupture (n=15)	Stent thrombosis (n=2)	Plaque erosion (n=1)	Fresh thrombus (n = 18)	Healing coronary thrombus (n=8)	P value †
Culprit lesion	13 (87)	2 (100)	0 (0)	15 (83)	2 (25)	0.004
Ischemic time (hours)*	24 (15–57)	49 (2− )	-	24 (12–65)	169 (144−)	0.0001
Mean lumen area	2.80 (1.91–4.40)	6.34 (6.00−)	2.01	3.24 (1.98–5.16)	5.53 (3.00–7.41)	0.068
Minimum lumen area	1.31 (0.99–2.57)	4.96 (4.74−)	1.55	1.84 (1.04–3.08)	3.36 (1.89–6.32)	0.095
Maximum lumen area	4.52 (3.03–7.47)	7.59 (5.51−)	2.60	4.83 (3.00–7.52)	8.03 (4.24–12.86)	0.055
Thrombus volume (mm3)	1.59 (1.05–3.20)	1.74 (1.21−)	0.22	1.48 (0.90–2.59)	2.8 (2.06–13.59)	0.074
Birefringence (Δn)	0.26 (0.17–0.31)	0.16 (0.12−)	0.25	0.25 (0.17–0.29)	0.47 (0.37–0.72)	0.007
Birefringence (Δn) staging
<0.25	7 (47)	2 (100)	0 (0)	9 (50)	0 (0)	0.023
0.25 – 0.40	7 (47)	0 (0)	1 (100)	8 (44)	2 (25)	0.420
>0.40	1 (6)	0 (0)	0 (0)	1 (6)	6 (75)	0.001
Depolarization	0.06 (0.05–0.08	0.16 (−0.28)	0.20	0.06 (0.05–0.12)	0.07 (0.05–0.08)	0.337

Values are median (IQR) or n (%).

^#fresh thrombus is comprised of plaque ruptures, erosions and stent thrombosis

^*only for thrombus-regions located in culprit lesions,

^†fresh thrombus as compared to healing coronary thrombus.