Table 2 –
Thrombus characteristics on a thrombus-region level
Variable | Plaque rupture (n=15) | Stent thrombosis (n=2) | Plaque erosion (n=1) | Fresh thrombus (n = 18) | Healing coronary thrombus (n=8) | P value † |
---|---|---|---|---|---|---|
Culprit lesion | 13 (87) | 2 (100) | 0 (0) | 15 (83) | 2 (25) | 0.004 |
Ischemic time (hours)* | 24 (15–57) | 49 (2− ) | - | 24 (12–65) | 169 (144−) | 0.0001 |
Mean lumen area | 2.80 (1.91–4.40) | 6.34 (6.00−) | 2.01 | 3.24 (1.98–5.16) | 5.53 (3.00–7.41) | 0.068 |
Minimum lumen area | 1.31 (0.99–2.57) | 4.96 (4.74−) | 1.55 | 1.84 (1.04–3.08) | 3.36 (1.89–6.32) | 0.095 |
Maximum lumen area | 4.52 (3.03–7.47) | 7.59 (5.51−) | 2.60 | 4.83 (3.00–7.52) | 8.03 (4.24–12.86) | 0.055 |
Thrombus volume (mm3) | 1.59 (1.05–3.20) | 1.74 (1.21−) | 0.22 | 1.48 (0.90–2.59) | 2.8 (2.06–13.59) | 0.074 |
Birefringence (Δn) | 0.26 (0.17–0.31) | 0.16 (0.12−) | 0.25 | 0.25 (0.17–0.29) | 0.47 (0.37–0.72) | 0.007 |
Birefringence (Δn) staging | ||||||
<0.25 | 7 (47) | 2 (100) | 0 (0) | 9 (50) | 0 (0) | 0.023 |
0.25 – 0.40 | 7 (47) | 0 (0) | 1 (100) | 8 (44) | 2 (25) | 0.420 |
>0.40 | 1 (6) | 0 (0) | 0 (0) | 1 (6) | 6 (75) | 0.001 |
Depolarization | 0.06 (0.05–0.08 | 0.16 (−0.28) | 0.20 | 0.06 (0.05–0.12) | 0.07 (0.05–0.08) | 0.337 |
Values are median (IQR) or n (%).
fresh thrombus is comprised of plaque ruptures, erosions and stent thrombosis
only for thrombus-regions located in culprit lesions,
fresh thrombus as compared to healing coronary thrombus.