Figure 8.
Effect of selected compounds [beauversetin (53), xanthoquinodin A1 (46), and metronidazole] on the growth and viability of L. acidophilus grown under anaerobic conditions. The tetramic-acid-containing compound (53) had no effect on the bacterium at the concentrations tested. In contrast, 46 exhibited significant inhibition of this important member of the vaginal microflora [data are expressed as the mean of triplicate experiments ± SD; DMSO (vehicle) did not exceed 1% by volume].