Table 2 –
Summary of worst adverse event per patient
| Relationship to treatment | Adverse event | Grade | RT + paclitaxel + trastuzumab (n = 20), n (%) |
RT + paclitaxel (n = 45), n (%) |
|---|---|---|---|---|
| Definitely, probably, or possibly | Worst nonhematological | 1 | 4 (20.0) | 10 (22.2%) |
| 2 | 4 (20.0) | 9 (20.0%) | ||
| 3 | 8 (40.0) | 7 (15.6%) | ||
| 4 | 1 (5.0) | 1 (2.2%) | ||
| 5 | 1 (5.0) | 0 (0%) | ||
| Worst overall | 1 | 0 (0.0) | 4 (8.9%) | |
| 2 | 4 (20.0) | 15 (33.3%) | ||
| 3 | 15 (75.0) | 22 (48.9%) | ||
| 4 | 0 (0.0) | 4 (8.9%) | ||
| 5 | 1 (5.0) | 0 (0.0%) | ||
| Any a | Worst nonhematological | 1 | 5 (25.0) | 10 (22.2%) |
| 2 | 4 (20.0) | 11 (24.4%) | ||
| 3 | 9 (45.0) | 10 (22.2%) | ||
| 4 | 1 (5.0) | 1 (2.2%) | ||
| 5 | 1 (5.0) | 0 (0%) | ||
| Worst overall | 1 | 0 (0.0) | 2 (4.4%) | |
| 2 | 4 (20.0) | 9 (20.0%) | ||
| 3 | 15 (75.0) | 26 (57.8%) | ||
| 4 | 0 (0.0) | 6 (13.3%) | ||
| 5 | 1 (5.0) | 2 (4.4%) |
CTCAE = Common Terminology Criteria for Adverse Events; RT = radiotherapy.
a
Includes adverse events where relationship to protocol treatment is missing. Adverse events were graded with CTCAE version 3.0.