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. Author manuscript; available in PMC: 2024 Sep 28.
Published in final edited form as: Cell. 2023 Sep 28;186(20):4422–4437.e21. doi: 10.1016/j.cell.2023.08.040

Figure 2. snATAC and snRNA integration enables peak-to-gene link calling.

Figure 2.

A. Schematic for the cell-type-specific integration framework.

B. UMAP of joint ATAC and RNA cell embedding (top) with major cell type assignments (bottom).

C. UMAP of joint embedding colored with the high-resolution sub-cell-type annotation.

D. Gene expression of marker genes across sub-cell-types in snRNA.

E. Estimated gene-score of marker genes across sub-cell-types in snATAC.

F. Recovery (AUPRC) of cell-type-specific PLAC-seq by inferred links (ABC: activity-by-contact method).

G. Precision-recall curves for cell-type-specific PLAC-seq.

H. GREAT enrichment of cell-type-specific ATAC modules.

See also Figure S2, Tables S3 and S4.