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. Author manuscript; available in PMC: 2024 Sep 28.
Published in final edited form as: Cell. 2023 Sep 28;186(20):4422–4437.e21. doi: 10.1016/j.cell.2023.08.040

Figure 5. AD-differential cell composition and ATAC changes.

Figure 5.

A. GREAT functional enrichments of AD-differentially accessible (*p<0.05, **p<0.01, ***p<0.001).

B. Major cell type compositional changes in snRNA-seq comparing non-AD, early-AD and late-AD participants (Anova using propeller). Right panel is the total number of cells.

C. Major cell type compositional changes in snATAC-seq.

D. Sub-cell-type compositional changes in snATAC-seq between non-AD, early-AD and late-AD participants (fractions within each major cell type).

See also Figure S5, Table S6.