Table 2:
Estimate (95% uncertainty interval) | |
---|---|
| |
Infectious disease | |
Infectious disease: acute episode, mild | 0·005 (0·002–0·011) |
Infectious disease: acute episode, moderate | 0·053 (0·033–0·081) |
Infectious disease: acute episode, severe | 0·210 (0·139–0·298) |
Infectious disease: post-acute consequences (fatigue, emotional lability, insomnia) | 0·254 (0·170–0·355) |
Diarrhoea: mild | 0·061 (0·036–0·093) |
Diarrhoea: moderate | 0·202 (0·133–0·299) |
Diarrhoea: severe | 0·281 (0·184–0·399) |
Epididymo-orchitis | 0·097 (0·063–0·137) |
Herpes zoster | 0·061 (0·039–0·094) |
HIV: symptomatic, pre-AIDS | 0·221 (0·146–0·310) |
HIV/AIDS: receiving antiretroviral treatment | 0·053 (0·034–0·079) |
AIDS: not receiving antiretroviral treatment | 0·547 (0·382–0·715) |
Intestinal nematode infections: symptomatic | 0·030 (0·016–0·048) |
Lymphatic filariasis: symptomatic | 0·110 (0·073–0·157) |
Ear pain | 0·018 (0·009–0·031) |
Tuberculosis: without HIV infection | 0·331 (0·222– 0·450) |
Tuberculosis: with HIV infection | 0·399 (0·267–0·547) |
Cancer | |
Cancer: diagnosis and primary therapy | 0·294 (0·199–0·411) |
Cancer: metastatic | 0·484 (0·330–0·643) |
Mastectomy | 0·038 (0·022–0·059) |
Stoma | 0·086 (0·055–0·131) |
Terminal phase: with medication (for cancers, end-stage kidney or liver disease) | 0·508 (0·348–0·670) |
Terminal phase: without medication (for cancers, end-stage kidney or liver disease) | 0·519 (0·356–0·683) |
Cardiovascular and circulatory disease | |
Acute myocardial infarction: days 1–2 | 0·422 (0·284–0·566) |
Acute myocardial infarction: days 3–28 | 0·056 (0·035–0·082) |
Angina pectoris: mild | 0·037 (0·022–0·058) |
Angina pectoris: moderate | 0·066 (0·043–0·095) |
Angina pectoris: severe | 0·167 (0·109–0·234) |
Cardiac conduction disorders and cardiac dysrhythmias | 0·145 (0·097–0·205) |
Claudication | 0·016 (0·008–0·028) |
Heart failure: mild | 0·037 (0·021–0·058) |
Heart failure: moderate | 0·070 (0·044–0·102) |
Heart failure: severe | 0·186 (0·128–0·261) |
Stroke: long-term consequences, mild | 0·021 (0·011–0·037) |
Stroke: long-term consequences, moderate | 0·076 (0·050–0·110) |
Stroke: long-term consequences, moderate plus cognition problems | 0·312 (0·211–0·433) |
Stroke: long-term consequences, severe | 0·539 (0·363–0·705) |
Stroke: long-term consequences, severe plus cognition problems | 0·567 (0·394–0·738) |
Diabetes, digestive, and genitourinary disease | |
Diabetic foot | 0·023 (0·012–0·039) |
Diabetic neuropathy | 0·099 (0·066–0·145) |
Chronic kidney disease (stage IV) | 0·105 (0·069–0·154) |
End-stage renal disease: with kidney transplant | 0·027 (0·015–0·043) |
End-stage renal disease: on dialysis | 0·573 (0·397–0·749) |
Decompensated cirrhosis of the liver | 0·194 (0·127–0·273) |
Gastric bleeding | 0·323 (0·214–0·461) |
Crohn’s disease or ulcerative colitis | 0·225 (0·152–0·314) |
Benign prostatic hypertrophy: symptomatic | 0·070 (0·046–0·102) |
Urinary incontinence | 0·142 (0·094–0·204) |
Impotence | 0·019 (0·010–0·034) |
Infertility: primary | 0·011 (0·005–0·021) |
Infertility: secondary | 0·006 (0·002–0·013) |
Chronic respiratory diseases | |
Asthma: controlled | 0·009 (0·004–0·018) |
Asthma: partially controlled | 0·027 (0·015–0·045) |
Asthma: uncontrolled | 0·132 (0·087–0·190) |
COPD and other chronic respiratory diseases: mild | 0·015 (0·007–0·028) |
COPD and other chronic respiratory diseases: moderate | 0·192 (0·129–0·271) |
COPD and other chronic respiratory diseases: severe | 0·383 (0·259–0·528) |
Neurological disorders | |
Dementia: mild | 0·082 (0·055–0·117) |
Dementia: moderate | 0·346 (0·233–0·475) |
Dementia: severe | 0·438 (0·299–0·584) |
Headache: migraine | 0·433 (0·287–0·593) |
Headache: tension-type | 0·040 (0·025–0·062) |
Multiple sclerosis: mild | 0·198 (0·137–0·278) |
Multiple sclerosis: moderate | 0·445 (0·303–0·593) |
Multiple sclerosis: severe | 0·707 (0·522–0·857) |
Epilepsy: treated, seizure free | 0·072 (0·047–0·106) |
Epilepsy: treated, with recent seizures | 0·319 (0·211–0·445) |
Epilepsy: untreated | 0·420 (0·279–0·572) |
Epilepsy: severe | 0·657 (0·464–0·827) |
Parkinson’s disease: mild | 0·011 (0·005–0·021) |
Parkinson’s disease: moderate | 0·263 (0·179–0·360) |
Parkinson’s disease: severe | 0·549 (0·383–0·711) |
Mental, behavioural, and substance use disorders | |
Alcohol use disorder: mild | 0·259 (0·176–0·359) |
Alcohol use disorder: moderate | 0·388 (0·262–0·529) |
Alcohol use disorder: severe | 0·549 (0·384–0·708) |
Fetal alcohol syndrome: mild | 0·017 (0·008–0·032) |
Fetal alcohol syndrome: moderate | 0·057 (0·036–0·087) |
Fetal alcohol syndrome: severe | 0·177 (0·117–0·255) |
Cannabis dependence | 0·329 (0·223–0·455) |
Amphetamine dependence | 0·353 (0·215–0·525) |
Cocaine dependence | 0·376 (0·235–0·553) |
Heroin and other opioid dependence | 0·641 (0·459–0·803) |
Anxiety disorders: mild | 0·030 (0·017–0·048) |
Anxiety disorders: moderate | 0·149 (0·101–0·210) |
Anxiety disorders: severe | 0·523 (0·365–0·684) |
Major depressive disorder: mild episode | 0·159 (0·107–0·223) |
Major depressive disorder: moderate episode | 0·406 (0·276–0·551) |
Major depressive disorder: severe episode | 0·655 (0·469–0·816) |
Bipolar disorder: manic episode | 0·480 (0·323–0·642) |
Bipolar disorder: residual state | 0·035 (0·021–0·055) |
Schizophrenia: acute state | 0·756 (0·571–0·894) |
Schizophrenia: residual state | 0·576 (0·399–0·756) |
Anorexia nervosa | 0·223 (0·151–0·313) |
Bulimia nervosa | 0·223 (0·150–0·310) |
Attention-deficit hyperactivity disorder | 0·049 (0·031–0·074) |
Conduct disorder | 0·236 (0·154–0·337) |
Asperger’s syndrome | 0·110 (0·073–0·157) |
Autism | 0·259 (0·177–0·362) |
Intellectual disability: mild | 0·031 (0·018–0·049) |
Intellectual disability: moderate | 0·080 (0·053–0·114) |
Intellectual disability: severe | 0·126 (0·085–0·176) |
Intellectual disability: profound | 0·157 (0·107–0·221) |
Hearing and vision loss | |
Hearing loss: mild | 0·005 (0·002–0·012) |
Hearing loss: moderate | 0·023 (0·013–0·038) |
Hearing loss: severe | 0·032 (0·018–0·051) |
Hearing loss: profound | 0·031 (0·018–0·049) |
Hearing loss: complete | 0·033 (0·020–0·052) |
Hearing loss: mild, with ringing | 0·038 (0·024–0·058) |
Hearing loss: moderate, with ringing | 0·058 (0·037–0·085) |
Hearing loss: severe, with ringing | 0·065 (0·041–0·094) |
Hearing loss: profound, with ringing | 0·088 (0·058–0·127) |
Hearing loss: complete, with ringing | 0·092 (0·061–0·134) |
Distance vision: mild impairment | 0·004 (0·001–0·010) |
Distance vision: moderate impairment | 0·033 (0·020–0·052) |
Distance vision: severe impairment | 0·191 (0·129–0·269) |
Distance vision blindness | 0·195 (0·132–0·272) |
Near vision impairment | 0·013 (0·006–0·024) |
Musculoskeletal disorders | |
Low back pain: acute, without leg pain | 0·269 (0·184–0·373) |
Low back pain: acute, with leg pain | 0·322 (0·219–0·447) |
Low back pain: chronic, without leg pain | 0·366 (0·248–0·499) |
Low back pain: chronic, with leg pain | 0·374 (0·252–0·506) |
Neck pain: acute, mild | 0·040 (0·023–0·064) |
Neck pain: acute, severe | 0·221 (0·150–0·305) |
Neck pain: chronic, mild | 0·101 (0·067–0·149) |
Neck pain: chronic, severe | 0·286 (0·197–0·398) |
Musculoskeletal problems: legs, mild | 0·023 (0·013–0·039) |
Musculoskeletal problems: legs, moderate | 0·079 (0·053–0·115) |
Musculoskeletal problems: legs, severe | 0·171 (0·117–0·240) |
Musculoskeletal problems: arms, mild | 0·024 (0·014–0·041) |
Musculoskeletal problems: arms, moderate | 0·114 (0·077–0·159) |
Musculoskeletal problems: generalised, moderate | 0·292 (0·197–0·410) |
Musculoskeletal problems: generalised, severe | 0·606 (0·421–0·771) |
Gout: acute | 0·293 (0·198–0·404) |
Injuries | |
Amputation of finger(s), excluding thumb: long term, with treatment | 0·030 (0·018–0·048) |
Amputation of thumb: long term | 0·013 (0·006–0·025) |
Amputation of one arm: long term, with or without treatment | 0·130 (0·088–0·185) |
Amputation of both arms: long term, with treatment | 0·044 (0·028–0·067) |
Amputation of both arms: long term, without treatment | 0·359 (0·242–0·497) |
Amputation of toe | 0·008 (0·003–0·017) |
Amputation of one leg: long term, with treatment | 0·021 (0·011–0·035) |
Amputation of one leg: long term, without treatment | 0·164 (0·111–0·229) |
Amputation of both legs: long term, with treatment | 0·051 (0·032–0·076) |
Amputation of both legs: long term, without treatment | 0·494 (0·341–0·654) |
Burns of <20% total surface area without lower airway burns: short term, with or without treatment | 0·096 (0·062–0·140) |
Burns of <20% total surface area or <10% total surface area if head or neck, or hands or wrist involved: long term, with or without treatment | 0·018 (0·010–0·032) |
Burns of ≥20% total surface area: short term, with or without treatment | 0·333 (0·220–0·472) |
Burns of ≥20% total surface area or ≥10% total surface area if head or neck, or hands or wrist involved: long term, with treatment | 0·127 (0·086–0·183) |
Burns of ≥20% total surface area or ≥10% total surface area if head or neck, or hands or wrist involved: long term, without treatment | 0·438 (0·298–0·588) |
Lower airway burns: with or without treatment | 0·373 (0·248–0·521) |
Crush injury: short or long term, with or without treatment | 0·145 (0·093–0·211) |
Dislocation of hip: long term, with or without treatment | 0·017 (0·008–0·030) |
Dislocation of knee: long term, with or without treatment | 0·129 (0·087–0·178) |
Dislocation of shoulder: long term, with or without treatment | 0·080 (0·053–0·116) |
Other injuries of muscle and tendon (includes sprains, strains, and dislocations other than shoulder, knee, or hip) | 0·009 (0·004–0·018) |
Drowning and non-fatal submersion: short or long term, with or without treatment | 0·288 (0·191–0·403) |
Fracture of clavicle, scapula, or humerus: short or long term, with or without treatment | 0·053 (0·033–0·080) |
Fracture of face bone: short or long term, with or without treatment | 0·173 (0·111– 0·257) |
Fracture of foot bones: short term, with or without treatment | 0·033 (0·019–0·053) |
Fracture of foot bones: long term, without treatment | 0·033 (0·019–0·052) |
Fracture of hand: short term, with or without treatment | 0·025 (0·013–0·043) |
Fracture of hand: long term, without treatment | 0·016 (0·008–0·028) |
Fracture of neck of femur: short term, with or without treatment | 0·308 (0·205–0·439) |
Fracture of neck of femur: long term, with treatment | 0·072 (0·047–0·105) |
Fracture of neck of femur: long term, without treatment | 0·388 (0·261–0·532) |
Fracture other than neck of femur: short term, with or without treatment | 0·192 (0·121–0·280) |
Fracture other than neck of femur: long term, without treatment | 0·053 (0·035–0·079) |
Fracture of patella, tibia or fibula, or ankle: short term, with or without treatment | 0·087 (0·055–0·127) |
Fracture of patella, tibia or fibula, or ankle: long term, with or without treatment | 0·070 (0·047–0·102) |
Fracture of pelvis: short term | 0·390 (0·257–0·545) |
Fracture of pelvis: long term | 0·194 (0·132–0·272) |
Fracture of radius or ulna: short term, with or without treatment | 0·065 (0·040–0·101) |
Fracture of radius or ulna: long term, without treatment | 0·050 (0·032–0·075) |
Fracture of skull: short or long term, with or without treatment | 0·073 (0·046–0·109) |
Fracture of sternum or fracture of one or two ribs: short term, with or without treatment | 0·150 (0·098–0·215) |
Fracture of vertebral column: short or long term, with or without treatment | 0·132 (0·085–0·195) |
Fractures: treated, long term | 0·003 (0·001–0·008) |
Injured nerves: short term | 0·065 (0·040–0·096) |
Injured nerves: long term | 0·136 (0·092–0·189) |
Injury to eyes: short term | 0·079 (0·050–0·118) |
Severe traumatic brain injury: short term, with or without treatment | 0·235 (0·156–0·331) |
Traumatic brain injury: long-term consequences, minor, with or without treatment | 0·106 (0·072–0·147) |
Traumatic brain injury: long-term consequences, moderate, with or without treatment | 0·224 (0·153–0·314) |
Traumatic brain injury: long-term consequences, severe, with or without treatment | 0·625 (0·444–0·789) |
Open wound: short term, with or without treatment | 0·005 (0·002–0·013) |
Poisoning: short term, with or without treatment | 0·171 (0·116–0·239) |
Severe chest injury: long term, with or without treatment | 0·056 (0·036–0·082) |
Severe chest injury: short term, with or without treatment | 0·352 (0·229–0·484) |
Spinal cord lesion below neck: treated | 0·047 (0·029–0·072) |
Spinal cord lesion below neck: untreated | 0·440 (0·290–0·588) |
Spinal cord lesion at neck: treated | 0·369 (0·243–0·513) |
Spinal cord lesion at neck: untreated | 0·673 (0·475–0·837) |
Other | |
Abdominopelvic problem: mild | 0·012 (0·005–0·023) |
Abdominopelvic problem: moderate | 0·123 (0·083–0·176) |
Abdominopelvic problem: severe | 0·326 (0·219–0·451) |
Anaemia: mild | 0·005 (0·002–0·011) |
Anaemia: moderate | 0·058 (0·038–0·086) |
Anaemia: severe | 0·164 (0·112–0·228) |
Periodontitis | 0·008 (0·003–0·017) |
Dental caries: symptomatic | 0·012 (0·005–0·023) |
Severe tooth loss | 0·072 (0·048–0·103) |
Disfigurement: level 1 | 0·013 (0·006–0·025) |
Disfigurement: level 2 | 0·072 (0·048–0·103) |
Disfigurement: level 3 | 0·398 (0·271–0·543) |
Disfigurement: level 1 with itch or pain | 0·029 (0·016–0·048) |
Disfigurement: level 2, with itch or pain | 0·187 (0·125–0·264) |
Disfigurement: level 3, with itch or pain | 0·562 (0·394–0·725) |
Generic uncomplicated disease: worry and daily medication | 0·031 (0·017–0·050) |
Generic uncomplicated disease: anxiety about diagnosis | 0·054 (0·033–0·082) |
Iodine-deficiency goitre | 0·200 (0·134–0·283) |
Kwashiorkor | 0·055 (0·033–0·085) |
Severe wasting | 0·127 (0·081–0·183) |
Speech problems | 0·054 (0·034–0·081) |
Motor impairment: mild | 0·012 (0·005–0·022) |
Motor impairment: moderate | 0·076 (0·050–0·109) |
Motor impairment: severe | 0·377 (0·251–0·518) |
Motor plus cognitive impairments: mild | 0·054 (0·033–0·084) |
Motor plus cognitive impairments: moderate | 0·221 (0·141–0·314) |
Motor plus cognitive impairments: severe | 0·425 (0·286–0·587) |
Rectovaginal fistula | 0·492 (0·330–0·660) |
Vesicovaginal fistula | 0·338 (0·228–0·467) |
COPD=chronic obstructive pulmonary disease.