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. Author manuscript; available in PMC: 2024 Jan 11.
Published in final edited form as: Lancet. 2012 Dec 15;380(9859):2129–2143. doi: 10.1016/S0140-6736(12)61680-8

Table 2:

Disability weights for 220 unique health states

Estimate (95% uncertainty interval)

Infectious disease
Infectious disease: acute episode, mild 0·005 (0·002–0·011)
Infectious disease: acute episode, moderate 0·053 (0·033–0·081)
Infectious disease: acute episode, severe 0·210 (0·139–0·298)
Infectious disease: post-acute consequences (fatigue, emotional lability, insomnia) 0·254 (0·170–0·355)
Diarrhoea: mild 0·061 (0·036–0·093)
Diarrhoea: moderate 0·202 (0·133–0·299)
Diarrhoea: severe 0·281 (0·184–0·399)
Epididymo-orchitis 0·097 (0·063–0·137)
Herpes zoster 0·061 (0·039–0·094)
HIV: symptomatic, pre-AIDS 0·221 (0·146–0·310)
HIV/AIDS: receiving antiretroviral treatment 0·053 (0·034–0·079)
AIDS: not receiving antiretroviral treatment 0·547 (0·382–0·715)
Intestinal nematode infections: symptomatic 0·030 (0·016–0·048)
Lymphatic filariasis: symptomatic 0·110 (0·073–0·157)
Ear pain 0·018 (0·009–0·031)
Tuberculosis: without HIV infection 0·331 (0·222– 0·450)
Tuberculosis: with HIV infection 0·399 (0·267–0·547)
Cancer
Cancer: diagnosis and primary therapy 0·294 (0·199–0·411)
Cancer: metastatic 0·484 (0·330–0·643)
Mastectomy 0·038 (0·022–0·059)
Stoma 0·086 (0·055–0·131)
Terminal phase: with medication (for cancers, end-stage kidney or liver disease) 0·508 (0·348–0·670)
Terminal phase: without medication (for cancers, end-stage kidney or liver disease) 0·519 (0·356–0·683)
Cardiovascular and circulatory disease
Acute myocardial infarction: days 1–2 0·422 (0·284–0·566)
Acute myocardial infarction: days 3–28 0·056 (0·035–0·082)
Angina pectoris: mild 0·037 (0·022–0·058)
Angina pectoris: moderate 0·066 (0·043–0·095)
Angina pectoris: severe 0·167 (0·109–0·234)
Cardiac conduction disorders and cardiac dysrhythmias 0·145 (0·097–0·205)
Claudication 0·016 (0·008–0·028)
Heart failure: mild 0·037 (0·021–0·058)
Heart failure: moderate 0·070 (0·044–0·102)
Heart failure: severe 0·186 (0·128–0·261)
Stroke: long-term consequences, mild 0·021 (0·011–0·037)
Stroke: long-term consequences, moderate 0·076 (0·050–0·110)
Stroke: long-term consequences, moderate plus cognition problems 0·312 (0·211–0·433)
Stroke: long-term consequences, severe 0·539 (0·363–0·705)
Stroke: long-term consequences, severe plus cognition problems 0·567 (0·394–0·738)
Diabetes, digestive, and genitourinary disease
Diabetic foot 0·023 (0·012–0·039)
Diabetic neuropathy 0·099 (0·066–0·145)
Chronic kidney disease (stage IV) 0·105 (0·069–0·154)
End-stage renal disease: with kidney transplant 0·027 (0·015–0·043)
End-stage renal disease: on dialysis 0·573 (0·397–0·749)
Decompensated cirrhosis of the liver 0·194 (0·127–0·273)
Gastric bleeding 0·323 (0·214–0·461)
Crohn’s disease or ulcerative colitis 0·225 (0·152–0·314)
Benign prostatic hypertrophy: symptomatic 0·070 (0·046–0·102)
Urinary incontinence 0·142 (0·094–0·204)
Impotence 0·019 (0·010–0·034)
Infertility: primary 0·011 (0·005–0·021)
Infertility: secondary 0·006 (0·002–0·013)
Chronic respiratory diseases
Asthma: controlled 0·009 (0·004–0·018)
Asthma: partially controlled 0·027 (0·015–0·045)
Asthma: uncontrolled 0·132 (0·087–0·190)
COPD and other chronic respiratory diseases: mild 0·015 (0·007–0·028)
COPD and other chronic respiratory diseases: moderate 0·192 (0·129–0·271)
COPD and other chronic respiratory diseases: severe 0·383 (0·259–0·528)
Neurological disorders
Dementia: mild 0·082 (0·055–0·117)
Dementia: moderate 0·346 (0·233–0·475)
Dementia: severe 0·438 (0·299–0·584)
Headache: migraine 0·433 (0·287–0·593)
Headache: tension-type 0·040 (0·025–0·062)
Multiple sclerosis: mild 0·198 (0·137–0·278)
Multiple sclerosis: moderate 0·445 (0·303–0·593)
Multiple sclerosis: severe 0·707 (0·522–0·857)
Epilepsy: treated, seizure free 0·072 (0·047–0·106)
Epilepsy: treated, with recent seizures 0·319 (0·211–0·445)
Epilepsy: untreated 0·420 (0·279–0·572)
Epilepsy: severe 0·657 (0·464–0·827)
Parkinson’s disease: mild 0·011 (0·005–0·021)
Parkinson’s disease: moderate 0·263 (0·179–0·360)
Parkinson’s disease: severe 0·549 (0·383–0·711)
Mental, behavioural, and substance use disorders
Alcohol use disorder: mild 0·259 (0·176–0·359)
Alcohol use disorder: moderate 0·388 (0·262–0·529)
Alcohol use disorder: severe 0·549 (0·384–0·708)
Fetal alcohol syndrome: mild 0·017 (0·008–0·032)
Fetal alcohol syndrome: moderate 0·057 (0·036–0·087)
Fetal alcohol syndrome: severe 0·177 (0·117–0·255)
Cannabis dependence 0·329 (0·223–0·455)
Amphetamine dependence 0·353 (0·215–0·525)
Cocaine dependence 0·376 (0·235–0·553)
Heroin and other opioid dependence 0·641 (0·459–0·803)
Anxiety disorders: mild 0·030 (0·017–0·048)
Anxiety disorders: moderate 0·149 (0·101–0·210)
Anxiety disorders: severe 0·523 (0·365–0·684)
Major depressive disorder: mild episode 0·159 (0·107–0·223)
Major depressive disorder: moderate episode 0·406 (0·276–0·551)
Major depressive disorder: severe episode 0·655 (0·469–0·816)
Bipolar disorder: manic episode 0·480 (0·323–0·642)
Bipolar disorder: residual state 0·035 (0·021–0·055)
Schizophrenia: acute state 0·756 (0·571–0·894)
Schizophrenia: residual state 0·576 (0·399–0·756)
Anorexia nervosa 0·223 (0·151–0·313)
Bulimia nervosa 0·223 (0·150–0·310)
Attention-deficit hyperactivity disorder 0·049 (0·031–0·074)
Conduct disorder 0·236 (0·154–0·337)
Asperger’s syndrome 0·110 (0·073–0·157)
Autism 0·259 (0·177–0·362)
Intellectual disability: mild 0·031 (0·018–0·049)
Intellectual disability: moderate 0·080 (0·053–0·114)
Intellectual disability: severe 0·126 (0·085–0·176)
Intellectual disability: profound 0·157 (0·107–0·221)
Hearing and vision loss
Hearing loss: mild 0·005 (0·002–0·012)
Hearing loss: moderate 0·023 (0·013–0·038)
Hearing loss: severe 0·032 (0·018–0·051)
Hearing loss: profound 0·031 (0·018–0·049)
Hearing loss: complete 0·033 (0·020–0·052)
Hearing loss: mild, with ringing 0·038 (0·024–0·058)
Hearing loss: moderate, with ringing 0·058 (0·037–0·085)
Hearing loss: severe, with ringing 0·065 (0·041–0·094)
Hearing loss: profound, with ringing 0·088 (0·058–0·127)
Hearing loss: complete, with ringing 0·092 (0·061–0·134)
Distance vision: mild impairment 0·004 (0·001–0·010)
Distance vision: moderate impairment 0·033 (0·020–0·052)
Distance vision: severe impairment 0·191 (0·129–0·269)
Distance vision blindness 0·195 (0·132–0·272)
Near vision impairment 0·013 (0·006–0·024)
Musculoskeletal disorders
Low back pain: acute, without leg pain 0·269 (0·184–0·373)
Low back pain: acute, with leg pain 0·322 (0·219–0·447)
Low back pain: chronic, without leg pain 0·366 (0·248–0·499)
Low back pain: chronic, with leg pain 0·374 (0·252–0·506)
Neck pain: acute, mild 0·040 (0·023–0·064)
Neck pain: acute, severe 0·221 (0·150–0·305)
Neck pain: chronic, mild 0·101 (0·067–0·149)
Neck pain: chronic, severe 0·286 (0·197–0·398)
Musculoskeletal problems: legs, mild 0·023 (0·013–0·039)
Musculoskeletal problems: legs, moderate 0·079 (0·053–0·115)
Musculoskeletal problems: legs, severe 0·171 (0·117–0·240)
Musculoskeletal problems: arms, mild 0·024 (0·014–0·041)
Musculoskeletal problems: arms, moderate 0·114 (0·077–0·159)
Musculoskeletal problems: generalised, moderate 0·292 (0·197–0·410)
Musculoskeletal problems: generalised, severe 0·606 (0·421–0·771)
Gout: acute 0·293 (0·198–0·404)
Injuries
Amputation of finger(s), excluding thumb: long term, with treatment 0·030 (0·018–0·048)
Amputation of thumb: long term 0·013 (0·006–0·025)
Amputation of one arm: long term, with or without treatment 0·130 (0·088–0·185)
Amputation of both arms: long term, with treatment 0·044 (0·028–0·067)
Amputation of both arms: long term, without treatment 0·359 (0·242–0·497)
Amputation of toe 0·008 (0·003–0·017)
Amputation of one leg: long term, with treatment 0·021 (0·011–0·035)
Amputation of one leg: long term, without treatment 0·164 (0·111–0·229)
Amputation of both legs: long term, with treatment 0·051 (0·032–0·076)
Amputation of both legs: long term, without treatment 0·494 (0·341–0·654)
Burns of <20% total surface area without lower airway burns: short term, with or without treatment 0·096 (0·062–0·140)
Burns of <20% total surface area or <10% total surface area if head or neck, or hands or wrist involved: long term, with or without treatment 0·018 (0·010–0·032)
Burns of ≥20% total surface area: short term, with or without treatment 0·333 (0·220–0·472)
Burns of ≥20% total surface area or ≥10% total surface area if head or neck, or hands or wrist involved: long term, with treatment 0·127 (0·086–0·183)
Burns of ≥20% total surface area or ≥10% total surface area if head or neck, or hands or wrist involved: long term, without treatment 0·438 (0·298–0·588)
Lower airway burns: with or without treatment 0·373 (0·248–0·521)
Crush injury: short or long term, with or without treatment 0·145 (0·093–0·211)
Dislocation of hip: long term, with or without treatment 0·017 (0·008–0·030)
Dislocation of knee: long term, with or without treatment 0·129 (0·087–0·178)
Dislocation of shoulder: long term, with or without treatment 0·080 (0·053–0·116)
Other injuries of muscle and tendon (includes sprains, strains, and dislocations other than shoulder, knee, or hip) 0·009 (0·004–0·018)
Drowning and non-fatal submersion: short or long term, with or without treatment 0·288 (0·191–0·403)
Fracture of clavicle, scapula, or humerus: short or long term, with or without treatment 0·053 (0·033–0·080)
Fracture of face bone: short or long term, with or without treatment 0·173 (0·111– 0·257)
Fracture of foot bones: short term, with or without treatment 0·033 (0·019–0·053)
Fracture of foot bones: long term, without treatment 0·033 (0·019–0·052)
Fracture of hand: short term, with or without treatment 0·025 (0·013–0·043)
Fracture of hand: long term, without treatment 0·016 (0·008–0·028)
Fracture of neck of femur: short term, with or without treatment 0·308 (0·205–0·439)
Fracture of neck of femur: long term, with treatment 0·072 (0·047–0·105)
Fracture of neck of femur: long term, without treatment 0·388 (0·261–0·532)
Fracture other than neck of femur: short term, with or without treatment 0·192 (0·121–0·280)
Fracture other than neck of femur: long term, without treatment 0·053 (0·035–0·079)
Fracture of patella, tibia or fibula, or ankle: short term, with or without treatment 0·087 (0·055–0·127)
Fracture of patella, tibia or fibula, or ankle: long term, with or without treatment 0·070 (0·047–0·102)
Fracture of pelvis: short term 0·390 (0·257–0·545)
Fracture of pelvis: long term 0·194 (0·132–0·272)
Fracture of radius or ulna: short term, with or without treatment 0·065 (0·040–0·101)
Fracture of radius or ulna: long term, without treatment 0·050 (0·032–0·075)
Fracture of skull: short or long term, with or without treatment 0·073 (0·046–0·109)
Fracture of sternum or fracture of one or two ribs: short term, with or without treatment 0·150 (0·098–0·215)
Fracture of vertebral column: short or long term, with or without treatment 0·132 (0·085–0·195)
Fractures: treated, long term 0·003 (0·001–0·008)
Injured nerves: short term 0·065 (0·040–0·096)
Injured nerves: long term 0·136 (0·092–0·189)
Injury to eyes: short term 0·079 (0·050–0·118)
Severe traumatic brain injury: short term, with or without treatment 0·235 (0·156–0·331)
Traumatic brain injury: long-term consequences, minor, with or without treatment 0·106 (0·072–0·147)
Traumatic brain injury: long-term consequences, moderate, with or without treatment 0·224 (0·153–0·314)
Traumatic brain injury: long-term consequences, severe, with or without treatment 0·625 (0·444–0·789)
Open wound: short term, with or without treatment 0·005 (0·002–0·013)
Poisoning: short term, with or without treatment 0·171 (0·116–0·239)
Severe chest injury: long term, with or without treatment 0·056 (0·036–0·082)
Severe chest injury: short term, with or without treatment 0·352 (0·229–0·484)
Spinal cord lesion below neck: treated 0·047 (0·029–0·072)
Spinal cord lesion below neck: untreated 0·440 (0·290–0·588)
Spinal cord lesion at neck: treated 0·369 (0·243–0·513)
Spinal cord lesion at neck: untreated 0·673 (0·475–0·837)
Other
Abdominopelvic problem: mild 0·012 (0·005–0·023)
Abdominopelvic problem: moderate 0·123 (0·083–0·176)
Abdominopelvic problem: severe 0·326 (0·219–0·451)
Anaemia: mild 0·005 (0·002–0·011)
Anaemia: moderate 0·058 (0·038–0·086)
Anaemia: severe 0·164 (0·112–0·228)
Periodontitis 0·008 (0·003–0·017)
Dental caries: symptomatic 0·012 (0·005–0·023)
Severe tooth loss 0·072 (0·048–0·103)
Disfigurement: level 1 0·013 (0·006–0·025)
Disfigurement: level 2 0·072 (0·048–0·103)
Disfigurement: level 3 0·398 (0·271–0·543)
Disfigurement: level 1 with itch or pain 0·029 (0·016–0·048)
Disfigurement: level 2, with itch or pain 0·187 (0·125–0·264)
Disfigurement: level 3, with itch or pain 0·562 (0·394–0·725)
Generic uncomplicated disease: worry and daily medication 0·031 (0·017–0·050)
Generic uncomplicated disease: anxiety about diagnosis 0·054 (0·033–0·082)
Iodine-deficiency goitre 0·200 (0·134–0·283)
Kwashiorkor 0·055 (0·033–0·085)
Severe wasting 0·127 (0·081–0·183)
Speech problems 0·054 (0·034–0·081)
Motor impairment: mild 0·012 (0·005–0·022)
Motor impairment: moderate 0·076 (0·050–0·109)
Motor impairment: severe 0·377 (0·251–0·518)
Motor plus cognitive impairments: mild 0·054 (0·033–0·084)
Motor plus cognitive impairments: moderate 0·221 (0·141–0·314)
Motor plus cognitive impairments: severe 0·425 (0·286–0·587)
Rectovaginal fistula 0·492 (0·330–0·660)
Vesicovaginal fistula 0·338 (0·228–0·467)

COPD=chronic obstructive pulmonary disease.