Fig. 6.

Stroke outcomes in IRF5 CKO and flox BM chimeras 3 days after MCAO. Data from chimeras of PB-to-IRF5 flox and CKO are presented (A–E) and data from chimeras of IRF5 flox and CKO-to-PB (F–J): A, F representative brain slices stained with Cresyl violet; infarct areas (white color) were circled with red dotted lines. B, G Quantification of infarct volumes. C, H Neurological deficit scores (NDS). D, I Corner test scores calculated by R/(R + L) × 100, where R and L indicate right and left turn number respectively. E, J Tape removal test. n = 6–7 per group for CV staining, NDS, and corner tests. n = 12–13 per group for tape removal test. *P < 0.05