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. Author manuscript; available in PMC: 2024 Jan 11.
Published in final edited form as: Nat Biomed Eng. 2022 Jul 4;6(7):791–805. doi: 10.1038/s41551-022-00902-5

Extended Data Fig. 3 |. Comparison of intranasal and inhalation immunization.

Extended Data Fig. 3 |

RBD-specific IgG antibodies in serum of mice and secretory IgA antibodies from BALF and NPLF of mice detected by ELISA, in which the mice were vaccinated with RBD-Exo VLP by intranasal administration or inhalation. Data are mean ± s.d. n = 3. Statistical analysis was performed by two-way ANOVA tests with a Tukey post hoc test for multiple comparisons. ns indicates no significance. All replicates are biological.