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Representative 3D image of the alveolar bone crest of control mice (A), mice with antigen-induced arthritis (AIA) (B) and AIA mice treated with methotrexate (MTX) (C). Quantification of alveolar bone crest loss on the palatal surface of the maxillary first, second and third molar regions. The region analysed is circled in red (D). Note: n = 5 animals per group; One-Way ANOVA (p < 0.05).
