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Diversity of gut microbiota. (A) Chao1 and Shannon alpha diversity index (B) Microbiota separation on the principal coordinates calculated from unweighted and (C) weighted UniFrac distances. Control animals, arthritis induced group (AIA) and animals with arthritis treated with methotrexate (AIA + MTX). Note: n = 4 to 16 animals per group; ns: non-significant.
