Table 3. Closest phenotypes to the node Seizure (HP:0001250) in the embedding space using the Cosine Similarity System, as shown in black, versus the Euclidean Distance System, as shown in blue.

While the two systems share most phenotypes, there are minor differences in phenotypes’ ranks.

Cosine Rank	Euclidian Rank	HPO	Closest Phenotypes Cosine.	Cosine Similarity	Euclidian Distance	Euclidian Rank	Cosine Rank	HPO	Closest Phenotypes Euclidian.	Cosine Similarity	Euclidian Distance
1	1	HP:0012638	Abnormal nervous system physiology	0.781	3.089	1	1	HP:0012638	Abnormal nervous system physiology	0.781	3.089
2	32	HP:0000707	Abnormality of the nervous system	0.705	4.078	2	5	HP:0020219	Motor seizure	0.644	3.297
3	3	HP:0011446	Abnormality of higher mental function	0.694	3.530	3	3	HP:0011446	Abnormality of higher mental function	0.694	3.530
4	5	HP:0002493	Upper motor neuron dysfunction	0.648	3.629	4	7	HP:0011442	Abnormal central motor function	0.614	3.603
5	2	HP:0020219	Motor seizure	0.644	3.297	5	4	HP:0002493	Upper motor neuron dysfunction	0.648	3.629
6	59	HP:0100022	Abnormality of movement	0.625	4.131	6	15	HP:0020221	Clonic seizure	0.509	3.695
7	4	HP:0011442	Abnormal central motor function	0.614	3.603	7	20	HP:0032855	Photosensitive myoclonic-tonic-clonic seizure	0.495	3.725
8	12	HP:0002527	Falls	0.583	3.906	8	14	HP:0004372	Reduced consciousness/confusion	0.521	3.783