TABLE 2.
Overexpressed efflux pump genes in INH mono-resistant isolates before and after drug induction a
| Sample ID | No drug induction | Efflux pump gene overexpression strain | One-half MIC of INH induction |
|---|---|---|---|
| HR-1 | / | N | / |
| HR-2 | Rv1250 | Y | / |
| HR-3 | Rv1250 and Rv0933 | Y | Rv3065, Rv2836, Rv1250, Rv0933, Rv1217c, and Rv1218c |
| HR-4 | Rv0933 | Y | Rv0933 |
| HR-5 | / | N | / |
| HR-6 | Rv0933 | Y | / |
| HR-7 | / | N | Rv1218c |
| HR-8 | Rv0933, Rv1217c, and Rv1218c | Y | Rv1250 and Rv0933 |
| HR-9 | Rv2836, Rv1250, Rv0933, Rv1217c, and Rv1218c | Y | / |
| HR-10 | Rv3065, Rv1250, and Rv0933 | Y | / |
| HR-11 | / | N | Rv3065 and Rv0933 |
| HR-12 | / | N | / |
| HR-13 | / | N | / |
| HR-14 | / | N | / |
| HR-15 | / | N | / |
| HR-16 | / | N | / |
| HR-17 | Rv0933 | Y | / |
| HR-18 | / | N | / |
a
HR represents INH mono-resistant strains. Y means Yes. N means No. "/" means that none of the 10 efflux pump genes is overexpressed.