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. 2023 Dec 8;12(1):e02399-23. doi: 10.1128/spectrum.02399-23

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Copyright © 2023 Song et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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Fig 5 — Serology responses of coronavirus-resistant subpopulations. Low antibody response to sCoV is associated with reduced rates of self-reported COVID-19. (A) Scatter plots between antibody abundance against SARS-CoV-2 and sCoV NC. (B) Overlap between subjects within the lowest fifth percentile of antibody levels indicates an unexpectedly large subpopulation of participants with low antibody response against both sCoV (Resistant Set 2) and SARS-CoV-2 NC (Resistant Set 1) (one-sided Fisher’s exact test). (C) Subjects with the lowest fifth percentile for both SARS-CoV-2 and human coronavirus (HCoV)-229E NC antibody levels were at increased likelihood for reporting to have never had COVID-19 (one-sided Fisher’s exact test). N denotes the number of subjects; X% denotes N as the percentage of the study population. SINR, spike-in normalized ratio.