Fig 3.

The sensitivity of the recombinant virus to ACV, PCV, GCV, and BVDU was determined in a plaque reduction assay on Vero cells (A, B, and C, upper panel) and HEL cells (D, E, F, and G, lower panel). The replication curves for each virus in the presence of the designated concentration of antiviral drug are shown. The number of plaques formed by each virus at the lowest drug concentration was almost identical to that formed by the mock (control). Each concentration was tested in triplicate, and the experiments were repeated independently three times. Data are presented as the mean ± standard deviation of the three repeat experiments.