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. 2023 Dec 15;12(1):e03966-23. doi: 10.1128/spectrum.03966-23

TABLE 1.

Genes significantly differentially expressed in K. pneumoniae ΔompR compared with WT, when co-incubated with a monolayer of human A549 lung epithelial cells a

Gene or locus tag log2FC Adjusted P-value (Predicted) function
mpR −6.827565916 7.00509E−86 Two-component system response regulator
mpK35 −3.259249606 1.68898E−34 Porin
dtpA −2.321517549 2.97161E−16 Dipeptide/tripeptide permease
mpC −1.757216339 0.000000947174 Porin
IT767_03325 −1.621397713 0.000015452404 Non-heme ferritin-like protein
IT767_02620 −1.511025745 0.000015452404 DNA-binding response regulator
mrkA −1.491525118 0.00176437549 Type 3 fimbria major subunit
ilvC −1.389780828 0.00546572241 Ketol-acid reductoisomerase
IT767_02625 −1.380606427 0.000503848469 DMT family transporter
rpsP −1.3772856 0.0263555292 30S ribosomal protein S16
IT767_15995 −1.342613157 0.0436857435 tRNA-Leu
deaD −1.31497228 0.0231368979 ATP-dependent RNA helicase
ychH 1.271180794 0.0253742485 Stress-induced protein
lldP 1.290650902 0.0264506555 L-Lactate permease
IT767_20215 1.336512105 0.0170453364 Aquaporin
araC 1.352973572 0.0170453364 Arabinose operon transcriptional regulator
IT767_11875 1.456031162 0.0180202346 YbgS-like family protein
csiE 1.479682873 0.00580507439 Stationary phase-inducible protein
raiA 1.611844528 0.000497823148 Ribosome-associated translation inhibitor
cspD 1.622883409 0.00278980858 Cold shock-like protein
phoH 1.648602795 0.00158781766 Phosphate starvation-inducible protein
mglB 1.837292397 0.000005778769 Galactose/glucose ABC transporter substrate-binding protein
IT767_08965 2.591391864 1.07569E−14 YmiA family putative membrane protein
a

Genes that are significantly differentially expressed (having an absolute log2FoldChange (log2FC) > log2(1.5) and an adjusted P < 0.05) in the ΔompR strain compared with the WT strain. For each gene, the function, the adjusted P-value, and log2FoldChange are given. For genes that have not been named, the predicted function (as per the published annotation) is given.