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. 2023 Dec 21;186(26):5910–5924.e17. doi: 10.1016/j.cell.2023.11.013

Figure 6.

Figure 6

3D analysis of developing cephalic arteries in human embryos

(A–D) Head and neck vascular segmentation in a PCW7 embryo immunostained for SMA (A, lateral view and B, frontal view), SOX9 (C) and PLVAP (D).

(E–H) Segmentation and mesh generation of the basilar artery (BA).

(I–K) Isolated segmented head and neck arterial vasculature with randomization of individual arterial segment colors is shown in frontal (I) and lateral (J) views. (K) shows head and neck arteries in conjunction with semi-transparent meshes of reference cartilaginous structures (white) and the choroid plexuses (green).

(L) Frontal view showing the right and left superior thyroid arteries (STAs) in relation to the thyroid cartilage (TC). Also showing the common carotid arteries (CCAs) and lingual arteries (LAs).

(M) Frontal view of the right (R VA) and left (L VA) vertebral arteries in relation to semi-transparent cervical vertebra (numbered C1–C7).

Related to Figure S7.

Scale bars: 2.5 mm in (A)–(C), (E), (J), and (K); 1 mm in (D); 500 μm in (F)–(H), (L), and (M); and 2 mm in (I).