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. 2024 Jan 11;19(1):e0296264. doi: 10.1371/journal.pone.0296264

Fig 5. Regulation of ECs and SMCs by fibroblasts.

Fig 5

A) Angiopoietin-like factors 1 and 2 secreted by maintenance, secretory, and ANGPTL7+ fibroblasts regulate ITGA5-expressing ECs and SMC1 as predicted by CellChat ligand-receptor interactome analysis. Arrows inside bubbles indicate the direction of regulation, with the size of the incoming arrow representing the strength of the interaction. B) Expression levels of ANGPTL1, ANGPTL2, and the alpha (ITGA5) and beta (ITGB1) subunits of the integrin receptor in ECs, SMCs, and fibroblasts.