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. 2024 Jan 11;19(1):e0296264. doi: 10.1371/journal.pone.0296264

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Fig 7 — A) Global plot of outgoing (ligand) and incoming (receptor) interactions among cell populations in veins as predicted by CellChat. Venous ECs are the top receivers among all populations. Valvular ECs are the top senders of signals. Monocytes/macrophages (Mo/Mφ) are the main immune populations participating as senders and receivers of global interactions. B) Examples of pathways where immune cells act as senders (left) or receivers (right) of signals. C) Plot of outgoing and incoming interactions among cell populations specifically for the chemokine (CXCL/CCL) signaling pathway. Venous ECs are the main receivers of signals through the ACKR1 receptor, while IL1B⁺ Mo/Mφ are the top senders. D) Relative contribution of specific chemokines to the plot in C. Red boxes indicate chemokines secreted by IL1B⁺ Mo/Mφ, while the green box marks chemokines secreted by venous/capillary ECs (CCL14) or other cells including venous ECs (CCL2).