Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Jan 9;57(1):124–140.e7. doi: 10.1016/j.immuni.2023.11.018

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2023 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Tcf1^hiCD69^hi NK cells share similarities with NK cells present in human skin

Analysis of single-cell gene expression of NK cells in human skin (data generated by Alkon et al.³²).

(A) UMAP showing re-clustering of NK cell clusters 0 and 3 from Figure S4A.

(B) Bubble plot representation of Z score of selected marker genes in murine (skin and spleen on day 25 pi, left) and human skin NK cells (CD56^bright- and CD56^dim-like subsets, right).

(C) UMAP representation of selected marker gene expression of human skin NK cells.

(D and E) Visualization of scores of gene expression in murine NK cells (D) and in human skin NK cell subsets (E). Scores were calculated based on genes significantly upregulated in indicated human skin NK cells, and then used to analyze murine NK cells (D) or based on genes associated to tissue-resident memory of T cells, as in Figure 3A, and then used to analyze human skin NK cells (E). See also Figure S4.