Table 4.
Association of polymorphisms in the study groups.
| Polymorphisms | Group |
OR (95%CI) | p- value | |
|---|---|---|---|---|
| Cases n (%) | Control n (%) | |||
| rs7975232 | ||||
| GG | 37 (18 %) | 23 (12 %) | REF | |
| GT | 104 (50 %) | 110 (55 %) | 0.55 (0.3,0.99) | 0.045 |
| TT | 61 (29 %) | 66 (33 %) | 0.52 (0.28,0.97) | 0.041 |
| G | 180 (43 %) | 154 (39 %) | REF | |
| T | 224 (54 %) | 244 (61 %) | 0.79 (0.59,1.04) | 0.093 |
| rs154410 | ||||
| GG | 57 (28 %) | 45 (23 %) | REF | |
| GA | 99 (48 %) | 85 (43 %) | 0.88 (0.63,1.25) | 0.481 |
| AA | 42 (20 %) | 60 (30 %) | 0.51 (0.34,0.76) | 0.001 |
| G | 215 (52 %) | 173 (43 %) | REF | |
| A | 181 (44 %) | 207 (52 %) | 0.7 (0.53,0.93) | 0.015 |
| rs 2,228,570 | ||||
| TT | 16 (8 %) | 17 (9 %) | REF | |
| TC | 83 (40 %) | 81 (41 %) | 1.08 (0.51,2.30) | 0.824 |
| CC | 102 (49 %) | 96 (48 %) | 1.12 (0.54,2.35) | 0.747 |
| T | 115 (28 %) | 115 (29 %) | REF | |
| C | 287 (69 %) | 273 (68 %) | 1.05 (0.77,1.42) | 0.750 |
| rs731236 | ||||
| TT | 98 (47 %) | 86 (43 %) | REF | |
| CT | 77 (37 %) | 79 (40 %) | 0.84 (0.62,1.13) | 0.248 |
| CC | 23 (11 %) | 32 (16 %) | 0.57 (0.37,0.88) | 0.012 |
| T | 275 (66 %) | 249 (62 %) | REF | |
| C | 121 (29 %) | 145 (36 %) | 0.76 (0.56,1.02) | 0.064 |
| rs7041 | ||||
| TT | 30 (14 %) | 37 (19 %) | REF | |
| GT | 99 (48 %) | 100 (50 %) | 1.22 (0.70,2.12) | 0.481 |
| GG | 72 (35 %) | 58 (29 %) | 1.53 (0.84,2.76) | 0.159 |
| T | 159 (38 %) | 174 (44 %) | REF | |
| G | 243 (59 %) | 216 (54 %) | 1.23 (0.93,1.63) | 0.149 |