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. 2023 Nov 29;79:101840. doi: 10.1016/j.molmet.2023.101840

Figure 4.

Figure 4

Effect of central TUG-905 administration on the hypothalamus of obese mice. (A) Representative immunoblot images and (B) densitometry quantification of protein levels of inflammation markers in the MBH (n = 7 mice/group) of vehicle and TUG-905 ICV-treated DIO mice. (C) Representative immunoblot images and (D) densitometry quantification of protein levels of pAMPK and ER stress markers in the MBH (n = 6–8 mice/group) of vehicle and TUG-905 ICV-treated DIO mice. Data are expressed as MEAN ± SEM. Statistical significance was determined by Student's t-test ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001 vs. vehicle.