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. 2024 Jan 11;7:14. doi: 10.1038/s42003-023-05642-z

Fig. 2. Per chromosome coverage in five individuals with aneuploidies on the sex chromosomes and in one individual with aneuploidy on chromosome 21 from this study.

Fig. 2

Proportion of sequences aligned on each chromosome, normalised between chromosomes and across individuals to account for differences in sequencing effort per library (Supplementary Data 3). Individuals C11119 (Sk4205 from Longwall Quad, Magdalen College), C10427 (WS224 from Wetwang Slack), C11569 (Sk30828 from Trinity Burial Ground) with a 47,XXY karyotype carried two copies of chromosome X as well as one copy of chromosome Y. Individual C10462 (WS267 from Wetwang Slack) carried a typical number of sex chromosomes (one X and one Y) and an extra copy of chromosome 21 resulting in a 47,XY, + 21 karyotype. Individual C13582 (Skeleton 16586 from Lincoln Eastern Bypass) had a 47,XYY karyotype, as indicated by the presence of only one copy of chromosome X and two copies of chromosome Y. Individual C10090 (CH163 from Charterhouse Warren) carried no copies of chromosome Y and one copy of chromosome X, with mosaicism (i.e. a minority of cells carried a 46,XX karyotype as evidenced by heterozygosity in chromosome X).