Table 4.
Metabolites that discriminate between Veillonella treatment and baseline and/or placebo
| Metabolite | Classification | Δ vs. Baseline (VIP Score) | Δ vs. Placebo (VIP Score) |
|---|---|---|---|
| 2-Piperidinone | -Derivative of piperidine (and other natural alkaloids) -Found in foods |
None | Decrease (1.96) |
| Alanine/Sarcosine | Amino acid | Decrease (2.63) | Decrease (1.99) |
| Aspartic Acid | Amino acid | Decrease (1.24) | None |
| Betaine | Osmolytes -Found in foods |
None | Decrease (3.41) |
| Cadaverine | Polyamine | Decrease (1.14) | None |
| Citric Acid | Aerobic metabolism intermediate -Found in foods |
Increase (1.68) | None |
| Glutamine | Amino acid | Decrease (1.42) | Decrease (1.60) |
| Leucine | Amino acid | None | Decrease (6.13) |
| Lysine | Amino acid | Decrease (1.32) | None |
| Nicotinic/Picolinic Acid | Tryptophan metabolite, vitamin B3 -Found in foods |
Increase (2.03) | None |
| Pipecolic Acid | Piperidine derivative (and other natural alkaloids) that assists in absorption of ions in the small intestine -Found in foods |
Decrease (2.56) | Decrease (2.15) |
| Suberic Acid | Derivative of oleic acid -Found in foods |
Decrease (1.15) | None |
| Threonine | Amino acid | Decrease (1.19) | None |
| Tyrosine | Amino acid | None | Decrease (2.60) |
VIP, variable importance in projection scores.