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. 2023 Dec 20;212(3):389–396. doi: 10.4049/jimmunol.2300639

FIGURE 5.

FIGURE 5.

MAIT cell PD-1 expression increases into 9 mo of COVID-19 convalescence. (A) Spearman correlation analysis of PD-1 expression on resting MAIT cells against GzmB response to IL-12+IL-18 stimulation or against (B) CD38 expression on MAIT cells sampled in 4-mo convalescent patients with COVID-19 (COV, orange) and HDs (blue). Correlation statistics for the COVID-19 convalescent group are indicated. (C) Relative frequencies of MAIT cell subsets, or (D) expression of activation markers, or (E) functionally relevant molecules in MAIT cells from HDs (n = 11) and convalescent patients with COVID-19 (n = 13) in the longitudinal cohort at 4- and 9-mo follow-up. Significance was evaluated by Kruskal–Wallis test followed by Dunn’s test with Benjamini–Hochberg adjustment of p values (*p < 0.05, **p < 0.01, ***p < 0.001).