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. 2023 Nov 16;27(1):17. doi: 10.3892/etm.2023.12305

Figure 7.

Figure 7

Schematic of the protective effect of TPL on AS-FLSs. TPL prevent the progression of AS by downregulating the expression of NONHSAT227927.1 and inhibiting the activation of the JAK3/STAT3 pathway, thereby improving the inflammatory response of AS-FLSs. TPL, triptolide; AS-FLS, Ankylosing spondylitis-Fibroblast-like synoviocyte; ESR, Erythrocyte sedimentation rate; CRP, C-reactive protein.