Table I.
Clinical immune-inflammatory markers and perception score of patients with AS and HCs.
| Parameter | AS (n=50) | HC (n=30) | t/F/χ2-value | P-value |
|---|---|---|---|---|
| Median age (IQR), years | 35 (30-45) | 34 (24-46) | 0.84 | 0.40 |
| Sex (%) | 1.00 | |||
| Male | 32(64) | 19 (63.33) | ||
| Female | 18(36) | 11 (36.67) | ||
| Median BMI (IQR) | 21.19 (18.39-23.80) | 20.34 (18.29-22.25) | 0.58 | 0.36 |
| Median disease duration (IQR), years | 12.00 (9.75-15.25) | NA | NA | |
| Median ESR (IQR), mm/h | 39.5 (21.50-58.00) | 5.00 (1.00-7.00) | 0.03 | <0.01b |
| CRP, mg/l | 34.20±28.30 | 6.35±4.57 | 51.50 | <0.01b |
| IgA, mmol/l | 4.58±5.67 | 1.01±0.81 | 17.88 | <0.01b |
| IgG, mmol/l | 11.06±2.98 | 8.41±1.07 | 12.08 | <0.01b |
| IgM, mmol/l | 1.49±0.81 | 1.00±0.45 | 6.27 | 0.01 |
| C3, g/l | 1.27 (1.13,1.40) | 1.21 (0.98,1.42) | 1.90 | 0.25 |
| C4, g/l | 0.35±0.17 | 0.38±0.20 | 0.64 | 0.43 |
| Median BASDAI score (IQR) | 4.4 (4.00-5.00) | NA | NA | |
| BASFI score | 4.70±0.53 | NA | NA | |
| BASMI score | 6.82±1.37 | NA | NA | |
| SAS score | 49.85±11.24 | 5.19±1.57 | 0.32 | 0.57 |
| Median SDS score (IQR) | 51.19 (41.71-73.32) | 7 (17.19-12.11) | 0.09 | <0.01a |
| Median VAS score (IQR) | 6.80 (5.82-7.28) | NA |
aP<0.05,
bP<0.001. Data are presented as the mean ± standard deviation. BMI, body mass index; SDS, Self-rating Depression Scale; SAS, Self-rating Anxiety Scale; VAS, Visual Analog Scale; BASDAI, Bath Ankylosing Spondylitis Disease Activity Index; BASFI, Bath Ankylosing Spondylitis Functional Index; BASMI, Bath Ankylosing Spondylitis Metrology Index; HC, Healthy control; NA, not applicable; ESR, Erythrocyte sedimentation rate; CRP, C-reactive protein.