TABLE 1.
Site | 22q11DS (n = 470) | Controls (n = 313) | p‐Value for sex | p‐Value for age | 22q11DS with IQ data (n = 442) | Controls with IQ data (n = 219) | p‐Value for sex | p‐Value for age | p‐Value for IQ | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sex (F/M) | Mean age (SD) | Sex (F/M) | Mean age (SD) | Sex (F/M) | Mean age (SD) | IQ (SD) | Sex (F/M) | Mean age (SD) | IQ (SD) | ||||||
All | 239/231 | 18.02 (9.20) | 143/170 | 18.21 (8.56) | .16 | .77 | 230/212 | 18.22 (8.66) | 75.13 (13.17) | 103/116 | 15.32 (6.28) | 111.67 (15.10) | .23 | .12 | <.001 |
Cardiff | 8/7 | 15.07 (2.87) | 6/5 | 14.55 (1.63) | .95 | .59 | 8/6 | 14.79 (2.75) | 77.36 (19.12) | 5/5 | 14.50 (1.72) | 106.70 (7.45) | .73 | .77 | <.001 |
UC Davis1 | 17/23 | 10.73 (2.06) | 18/19 | 10.43 (2.46) | .59 | .57 | 17/23 | 10.73 (2.06) | 72.65 (13.28) | 16/17 | 10.21 (2.48) | 114.70 (11.07) | .61 | .34 | <.001 |
UC Davis2 | 30/34 | 11.34 (2.52) | 23/25 | 10.83 (2.39) | .91 | .28 | 28/34 | 11.35 (2.55) | 75.48 (13.15) | 22/23 | 10.78 (2.40) | 113.73 (14.64) | .70 | .24 | <.001 |
IoP, London | 17/19 | 16.83 (7.19) | 15/10 | 19.64 (6.05) | .33 | .12 | 17/19 | 16.83 (7.19) | 84.50 (13.07) | 15/10 | 19.64 (6.05) | 115.88 (10.28) | .33 | .16 | <.001 |
Maastricht | 13/14 | 29.22 (6.70) | 15/30 | 29.27 (9.62) | .21 | .98 | 13/14 | 29.22 (6.70) | 74.48 (11.30) | 5/18 | 24.43 (7.70) | 108.35 (15.82) | .05 | .02 | <.001 |
Newcastle | 12/7 | 17.21 (2.92) | 14/12 | 16.77 (3.30) | .53 | .64 | 12/7 | 17.21 (2.92) | 73.74 (13.56) | 13/11 | 16.63 (3.37) | 108.67 (15.71) | .55 | .55 | <.001 |
SUNY | 24/30 | 20.72 (2.33) | 8/12 | 20.50 (1.24) | .73 | .69 | 24/30 | 20.72 (2.33) | 73.65 (11.29) | 8/12 | 20.50 (1.24) | 105.20 (14.10) | .73 | .69 | <.001 |
Toronto1 | 7/8 | 41.47 (7.58) | 4/8 | 42.42 (8.67) | .48 | .76 | 7/8 | 41.47 (7.58) | 72.00 (10.69) | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ |
Toronto2 | 21/13 | 28.03 (10.26) | ‐ | ‐ | ‐ | ‐ | 20/13 | 28.09 (10.42) | 71.67 (9.85) | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ |
UCLA1 | 12/14 | 14.69 (6.79) | 15/7 | 14.50 (5.79) | .13 | .92 | 11/13 | 13.50 (5.36) | 81.58 (14.15) | 14/7 | 13.95 (5.31) | 119.05 (20.58) | .16 | .78 | <.001 |
UCLA2 | 21/17 | 15.84 (7.93) | 5/14 | 13.26 (3.60) | .04 | .18 | 21/15 | 15.47 (6.94) | 77.61 (12.15) | 5/13 | 12.89 (3.31) | 104.67 (17.83) | .03 | .14 | <.001 |
UPenn | 19/30 | 17.29 (3.20) | 20/28 | 17.52 (3.22) | .77 | .72 | 14/15 | 17.62 (2.98) | 76.31 (18.58) | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ |
Utrecht | 38/15 | 17.57 (4.22) | ‐ | ‐ | ‐ | ‐ | 38/15 | 17.57 (4.22) | 69.74 (8.54) | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ |
Abbreviations: 22q11DS, 22q11 deletion syndrome; IoP, Institute of Psychiatry; IQ, intelligence quotient; SUNY, State University of New York; UC Davis, University of California Davis; UCLA, University of California, Los Angeles; Upenn, University of Pennsylvania.