Fig. 5.

Histological examination of liver, kidney and pancreatic tissue (magnification × 100) after hematoxylin and eosin staining. Liver: Normal hepatocytes in control, glibenclamide and PF treated groups (low, middle, and high) are indicated by orange arrow. Whereas lipid droplets in HFD group, glibenclamide and PF treated groups are indicated by green arrow. HFD= High Fat Diet; PF= Polyherbal Formulation. Kidney: Normal glomerulus is shown by asterisk mark in control, glibenclamide and PF treated groups (low, middle, and high). Increased bowman's space in HFD group is shown by orange arrows. Pancreas: Arrows indicates acini in all studied groups, whereas asterisk mark indicates islet of langerhans in pancreas of control, glibenclamide and PF treated groups (125, 250, 500 mg/kg). The large view of changes has been shown with the help of inset (scale bar = 20 μm). A).