Table 2.

Correlation and regression analysis between serum eccDNA SORBS1^circle level and other clinical and biochemical parameters

Varibles	Pearson correlation		Multiple linear regression
	R value	P value	β value	T value	P value
Age	− 0.015	0.880
Sex	− 0.069	0.484
BMI	0.123	0.211
SBP	0.014	0.888
DBP	− 0.011	0.913
FBG	0.351	0.000**	0.079	1.124	0.264
2 hPBG	0.177	0.069	0.109	1.692	0.094
HbA1c	0.257	0.008**	0.141	2.193	0.031*
FIns	0.629	0.000**	− 0.069	− 0.544	0.588
2 hPIns	0.059	0.548
HOMA-IR	0.751	0.000**	0.751	11.593	0.000**
HOMA-β	0.177	0.069	− 0.067	− 0.982	0.329
TC	0.073	0.458
TG	0.106	0.278
HDL-C	− 0.091	0.354
LDL-C	− 0.003	0.978
ALT	0.005	0.962
AST	− 0.023	0.819
Cr	− 0.025	0.798
UA	− 0.153	0.117

*P < 0.05, **P < 0.01. BMI Body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, FBG fasting blood glucose, 2 hPBG 2-h postprandial blood glucose, HbA1c glycosylated hemoglobin A1c, FIns fasting insulin, 2 hPIns 2-h postprandial insulin, HOMA-IR homeostasis model assessment of insulin resistance, HOMA-β homeostasis model assessment of islet β-cell function, TC total cholesterol, TG triglycerides, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, ALT alanine transaminase, AST aspartate transaminase, Cr creatinine, UA uric acid