TABLE 1.
Compound | Concn (mM) | No. of replicates | OD
|
||
---|---|---|---|---|---|
Mean | SEM | % Change | |||
OHHL | 0.1 | 4 | 0.08 | 0.001 | 0.4 |
0.01 | 4 | 0.08 | 0.003 | 0.3 | |
0.001 | 4 | 0.08 | 0.001 | −1.0 | |
0.0001 | 4 | 0.08 | 0.002 | −0.1 | |
OdDHL | 0.1 | 4 | 0.12 | 0.004 | −7.8 |
0.01 | 4 | 0.08 | 0.003 | −0.4 | |
0.001 | 4 | 0.08 | 0.001 | 0 | |
0.0001 | 4 | 0.08 | 0.001 | 0.4 | |
DMSO | 0.1b | 4 | 0.08 | 0.001 | −0.8 |
0.01b | 4 | 0.08 | 0.001 | 0 | |
0.001b | 4 | 0.08 | 0.001 | −0.5 | |
0.0001b | 4 | 0.08 | 0.001 | 0.1 | |
Cells alone | 8 | 0.08 | 0.001 | 0 | |
Lysis control | 8 | 0.58 | 0.019 | −100** |
Statistical analysis by one-way analysis of variance of OD data, followed by Dunnett’s test. **, P < 0.01.
Dimethyl sulfoxide (DMSO) control diluted the same as equivalent compound concentrations. No significance was noted with the small changes in calculated viability.